SCHEMBL28290339

SCHEMBL28290339

CCCCC1C(C(N)=O)C(C(N)=O)CN1CCCC

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
OGA O60502 1/20 0.39
GBA2 Q9HCG7 14/20 0.39
GAA P10253 5/20 0.39
GBA1 P04062 4/20 0.39
UGCG Q16739 3/20 0.39
MGAM O43451 2/20 0.39
SI P14410 2/20 0.39
AGL P35573 2/20 0.39
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
KMT2A Q03164 1/20 0.38
BCHE P06276 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28290325 0.98 GAA (0.40) OGAGBA2GAAGBA1UGCG
SCHEMBL28640358 0.91 BCHE (0.42) GBA2GAAGBA1UGCGBCHE
SCHEMBL28291787 0.91 BCHE (0.42) GBA2GAAGBA1UGCGBCHE
SCHEMBL28629201 0.91 BCHE (0.42) GBA2GAAGBA1UGCGBCHE
SCHEMBL28291782 0.91 BCHE (0.42) GBA2GAAGBA1UGCGBCHE
SCHEMBL28640509 0.91 BCHE (0.42) GBA2GAAGBA1UGCGBCHE
Hydrochloric Acid SCHEMBL28630329 0.90 BCHE (0.41) GBA2GAAGBA1UGCGBCHE
Hydrochloric Acid SCHEMBL28627124 0.90 BCHE (0.41) GBA2GAAGBA1UGCGBCHE
Hydrochloric Acid SCHEMBL28635761 0.90 BCHE (0.41) GBA2GAAGBA1UGCGBCHE
Hydrochloric Acid SCHEMBL28626843 0.90 BCHE (0.41) GBA2GAAGBA1UGCGBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641878-B DIPROVOCIM: effective TLR agonist 斯克里普斯研究学院 2021-09-14 CN disclosed
CN-109641878-A DIPROVOCIM: a new class of effective TLR agonist 斯克里普斯研究学院 2019-04-16 CN disclosed