Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MC4R | P32245 | 2/20 | 0.58 |
| ▸ | MC5R | P33032 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18823346 | 0.88 | CHRM2 (0.59) | SMN1; SMN2MC4RMC5RHDAC1MAOA | |
| SCHEMBL167415 | 0.87 | MEN1 (0.73) | MC4RMC5RMEN1KMT2ATDP1 | |
| SCHEMBL16812954 | 0.87 | SMN1; SMN2 (0.75) | SMN1; SMN2MEN1KMT2ATDP1MAOA | |
| SCHEMBL10045136 | 0.86 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1KMT2ATDP1MAOA | |
| Ammonia Solution, Strong SCHEMBL20357468 | 0.85 | MEN1 (0.70) | MC4RMC5RHDAC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10382368 | 0.85 | MEN1 (0.70) | MC4RMC5RHDAC1MEN1KMT2A | |
| SCHEMBL9631654 | 0.85 | MEN1 (0.70) | MC4RMC5RHDAC1MEN1KMT2A | |
| SCHEMBL13521675 | 0.85 | MC4R (0.61) | SMN1; SMN2MC4RMC5RMEN1KMT2A | |
| SCHEMBL4909407 | 0.83 | TDP1 (0.74) | SMN1; SMN2MC4RMC5RMEN1KMT2A | |
| SCHEMBL4916283 | 0.83 | TDP1 (0.74) | SMN1; SMN2MC4RMC5RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-A | modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2019-04-02 | — | — | CN | disclosed |