Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27484195 | 0.88 | TACR1 (0.42) | TACR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| Piperazine SCHEMBL28083640 | 0.88 | TACR1 (0.42) | TACR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| Piperazine SCHEMBL28258210 | 0.86 | TACR1 (0.41) | TACR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| Pyrrolidine SCHEMBL27776262 | 0.85 | TACR1 (0.41) | TACR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| Tetrahydrofuran SCHEMBL27396831 | 0.85 | MEN1 (0.43) | MEN1KMT2ANPSR1TSHRALDH1A1 | |
| Azetidine SCHEMBL27976635 | 0.84 | TSHR (0.41) | TACR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| Azepane SCHEMBL27704297 | 0.83 | TACR1 (0.40) | TACR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| Piperidine SCHEMBL6727375 | 0.83 | TACR1 (0.40) | TACR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| Fluoride SCHEMBL27488772 | 0.82 | TSHR (0.50) | MEN1KMT2ASLC6A2SLC6A3TSHR | |
| Piperidine SCHEMBL27922706 | 0.82 | TSHR (0.40) | TACR1HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715612-A | SOMATOSTATIN MODULATORS AND USES THEREOF | 克林提克斯医药股份有限公司 | 2019-05-03 | — | — | CN | disclosed |