Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.74 |
| ▸ | CDK2 | P24941 | 3/20 | 0.74 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.74 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.74 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.64 |
| ▸ | WNT1 | P04628 | 3/20 | 0.64 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.59 |
| ▸ | CLK2 | P49760 | 2/20 | 0.58 |
| ▸ | CLK3 | P49761 | 2/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.58 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951125 | 0.86 | FLT3 (1.00) | FLT3CDK2CCNA2CCNA1MAP4K1 | |
| SCHEMBL30398090 | 0.86 | FLT3 (1.00) | FLT3CDK2CCNA2CCNA1MAP4K1 | |
| SCHEMBL30026349 | 0.85 | FLT3 (0.81) | FLT3CDK2CCNA2CCNA1MAP4K1 | |
| SCHEMBL5945670 | 0.84 | DYRK1A (0.65) | FLT3CDK2CCNA2CCNA1DYRK1A | |
| SCHEMBL5945656 | 0.84 | DYRK1A (0.64) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14785616 | 0.84 | DYRK1A (0.64) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL14785604 | 0.83 | DYRK1A (0.84) | DYRK1AWNT1CLK2CLK3 | |
| SCHEMBL4523169 | 0.81 | FLT3 (0.89) | FLT3CDK2CCNA2CCNA1MAP4K1 | |
| SCHEMBL14699293 | 0.80 | ITK (0.82) | FLT3CDK2CCNA2CCNA1CSNK2A1 | |
| SCHEMBL6223964 | 0.79 | DYRK1A (0.78) | DYRK1AWNT1CLK2CLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109705097-A | Indazole -3- carboxylic acid amides and its purposes as WNT/ β-CATENIN signal transduction pathway inhibitor | 萨穆梅德有限公司 | 2019-05-03 | — | — | CN | disclosed |