Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292690 | 0.82 | ESR1 (0.44) | ESR1ESR2NPC1RAB9AAPP | |
| SCHEMBL29404012 | 0.79 | ESR1 (0.65) | ESR1ESR2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL244496 | 0.79 | ESR1 (0.65) | ESR1ESR2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29459501 | 0.79 | ESR1 (0.65) | ESR1ESR2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28872623 | 0.76 | ESR2 (0.53) | ESR1ESR2 | |
| SCHEMBL21538491 | 0.71 | ESR1 (0.69) | ESR1ESR2ALDH1A1KDM4ELMNA | |
| SCHEMBL11320611 | 0.69 | NPC1 (0.59) | ESR1ESR2MAPTSNCANPC1 | |
| SCHEMBL26660250 | 0.69 | MAPT (0.54) | ESR1ESR2MAPTSNCANPC1 | |
| SCHEMBL7909628 | 0.68 | ESR1 (0.63) | ESR1ESR2APP | |
| SCHEMBL296382 | 0.68 | ESR1 (0.63) | ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105899497-B | Novel bis (hydroxyphenyl) benzoxazole compounds | 本州化学工业株式会社 | 2019-04-09 | — | — | CN | disclosed |