⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833869 | 0.87 | PTGS1 (0.36) | — | |
| SCHEMBL22771248 | 0.85 | HSD17B10 (0.35) | — | |
| SCHEMBL23733923 | 0.80 | CYP2C19 (0.42) | — | |
| SCHEMBL11572382 | 0.76 | — | — | |
| SCHEMBL238623 | 0.76 | — | — | |
| SCHEMBL12600744 | 0.76 | — | — | |
| SCHEMBL26928 | 0.75 | — | — | |
| SCHEMBL9578246 | 0.74 | — | — | |
| SCHEMBL380859 | 0.74 | — | — | |
| SCHEMBL175335 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945611-B1 | N- (HETERO) ARYL INDOLE DERIVATIVES AS PESTICIDES | NOVARTIS AG (CH) | 2010-01-06 | — | — | EP | claimed |
| US-20090227538-A1 | N-(Hetero)Aryl Indole Derivatives as Pesticides | NOVARTIS AG (CH) | 2009-09-10 | — | — | US | claimed |
| EP-1945611-A1 | N- (HETERO) ARYL INDOLE DERIVATIVES AS PESTICIDES | Novartis Pharma AG (CH) | 2008-07-23 | — | — | EP | claimed |
| WO-2007051619-A1 | N- (HETERO) ARYL INDOLE DERIVATIVES AS PESTICIDES | NOVARTIS AG (CH) | 2007-05-10 | — | — | WO | claimed |
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | claimed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | claimed |
| US-4654435-A | WITH ORGANIC COMPOUNDS HAVING BOTH A CARBOXYL GROUP AND AN ALDEHYDE GROUP | NIPPON ZEON CO., LTD. (JP) | 1987-03-31 | — | — | US | claimed |
| CN-116744935-B | Benzazepine compound, preparation method and medical application thereof | 福建盛迪医药有限公司 | 2026-05-12 | — | — | CN | disclosed |
| US-11981750-B2 | Antigenic tripeptides derived from Mycobacterium avium subsp. paratuberculosis s-type strains, derivatives and uses thereof | INSTITUT PASTEUR (FR) | 2024-05-14 | — | — | US | disclosed |
| US-20230321287-A1 | RADIOLABELLED GRPR-ANTAGONIST FOR USE AS THERAGNOSTIC | NOVARTIS AG (CH) | 2023-10-12 | — | — | US | disclosed |
| CN-116744935-A | Benzazepine compound, preparation method and medical application thereof | 上海森辉医药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| EP-4159795-A1 | THERAPEUTIC CONJUGATES WITH SULFATED DENDRIMERS FOR INTRACELLULAR TARGETING | ICD-Therapeutics GmbH (DE) | 2023-04-05 | — | — | EP | disclosed |
| US-20230046953-A1 | ANTIGENIC TRIPEPTIDES DERIVED FROM MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS S-TYPE STRAINS, DERIVATIVES AND USES THEREOF | PASTEUR INSTITUT (FR) | 2023-02-16 | — | — | US | disclosed |
| EP-0087109-B1 | MODIFIED RUBBER COMPOSITION | NIPPON ZEON CO., LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0087110-B1 | PROCESS FOR MODIFYING RUBBERS | NIPPON ZEON CO., LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |
| US-4487715-A | ACTIVATION, ESTERIFICATION, IMMOBILIZATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-12-11 | — | — | US | disclosed |
| US-4412031-A | CARBON BLACK | NIPPON ZEON CO., LTD. (JP) | 1983-10-25 | — | — | US | disclosed |
| US-4412041-A | IN PRESENCE OF ACID CATALYSTS | NIPPON ZEON CO. LTD. (JP) | 1983-10-25 | — | — | US | disclosed |
| EP-0087109-A1 | Modified rubber composition | NIPPON ZEON CO., LTD. (JP) | 1983-08-31 | — | — | EP | disclosed |
| EP-0087110-A1 | Process for modifying rubbers | NIPPON ZEON CO., LTD. (JP) | 1983-08-31 | — | — | EP | disclosed |