Pyridine-2,5-Dicarboxylic Acid

Pyridine-2,5-Dicarboxylic Acid

SCHEMBL28292038

O=C(O)c1ccc(C(=O)O)nc1.[Zr]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 13/20 0.95
P4HA1 P13674 2/20 0.95
MIF P14174 1/20 0.95
KDM4E B2RXH2 2/20 0.63
MAPK1 P28482 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
ALDH1A1 P00352 2/20 0.57
GABRP O00591 1/20 0.57
GABRD O14764 1/20 0.57
GABRA1 P14867 1/20 0.57
GABRB1 P18505 1/20 0.57
GABRG2 P18507 1/20 0.57
GABRB3 P28472 1/20 0.57
GABRA5 P31644 1/20 0.57
GABRA3 P34903 1/20 0.57
GABRA2 P47869 1/20 0.57
GABRB2 P47870 1/20 0.57
GABRA4 P48169 1/20 0.57
GABRE P78334 1/20 0.57
GABRA6 Q16445 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine-2,5-Dicarboxylic Acid SCHEMBL29363410 0.98 P4HTM (1.00) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL70231 0.98 P4HTM (1.00) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL9367780 0.95 P4HTM (0.95) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL21173963 0.95 P4HTM (0.95) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL28522095 0.95 P4HTM (0.95) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL2275972 0.95 P4HTM (0.95) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL11489139 0.95 P4HTM (0.95) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL9341728 0.95 P4HTM (0.95) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL336436 0.95 P4HTM (0.95) P4HTMP4HA1MIFKDM4EMAPK1
Pyridine-2,5-Dicarboxylic Acid SCHEMBL7655946 0.95 P4HTM (0.95) P4HTMP4HA1MIFKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109675638-A A kind of composite catalyzing material, preparation method and dehydrogenation hydrogenation reaction mediates the application prepared in 2,5- dimethyl furan in situ 淮阴师范学院 2019-04-26 CN claimed
CN-109675638-B Composite catalytic material, preparation method and application in-situ dehydrogenation hydrogenation reaction mediated preparation of 2, 5-dimethylfuran 淮阴师范学院 2021-08-13 CN disclosed
CN-109675638-A A kind of composite catalyzing material, preparation method and dehydrogenation hydrogenation reaction mediates the application prepared in 2,5- dimethyl furan in situ 淮阴师范学院 2019-04-26 CN disclosed