Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | GPR3 | P46089 | 1/20 | 0.52 |
| ▸ | LPL | P06858 | 5/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28051879 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL28051878 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL28051881 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL28051684 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL28051688 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL28051683 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL28051685 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL5012393 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL28825910 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL28051876 | 1.00 | HTR2A (0.56) | HTR2ASLC6A2SLC6A4HTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330508-B | One kind 3 is monosubstituted or 3,6 2 replace fluorene derivative and its preparation method and application | 亚培烯科技（杭州）有限公司 | 2019-04-19 | — | — | CN | disclosed |