Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291347 | 0.81 | SRD5A2 (0.35) | SRD5A2PROKR1 | |
| SCHEMBL20971740 | 0.78 | NR1H2 (0.55) | SRD5A2MAPTNR1H2 | |
| SCHEMBL11364687 | 0.70 | MAPT (0.60) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL274525 | 0.69 | NR1H2 (0.50) | ALDH1A1MAPTMAPK1GFERNR1H2 | |
| SCHEMBL29959037 | 0.69 | NR1H2 (0.50) | ALDH1A1MAPTMAPK1GFERNR1H2 | |
| SCHEMBL15536669 | 0.69 | PROKR1 (0.32) | PROKR1ALDH1A1MAPK1 | |
| SCHEMBL15530574 | 0.68 | HTR1D (0.39) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL28291353 | 0.66 | MC4R (0.31) | — | |
| SCHEMBL17713023 | 0.65 | GRIN2D (0.44) | SRD5A2ALDH1A1LMNAMAPTGRIN2D | |
| SCHEMBL4245359 | 0.64 | SMN1; SMN2 (0.45) | SRD5A2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661392-A | For treating the mitochondrial inhibitors of proliferative disorder | 巴斯利尔药物国际股份公司 | 2019-04-19 | — | — | CN | disclosed |