SCHEMBL28293902

SCHEMBL28293902

CC(C)Oc1ccccc1C(=O)[SiH3]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.70
ALDH1A1 P00352 3/20 0.51
ACHE P22303 1/20 0.51
IDO1 P14902 1/20 0.50
TDO2 P48775 1/20 0.50
KCNK3 O14649 2/20 0.48
KCNK9 Q9NPC2 2/20 0.48
KDM4E B2RXH2 4/20 0.44
LMNA P02545 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
PRMT5 O14744 1/20 0.43
MRGPRX1 Q96LB2 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC4 P56524 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7088362 0.86 IRAK4 (0.72) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL2094692 0.86 IRAK4 (0.72) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL104892 0.84 IRAK4 (0.70) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL7058906 0.83 IRAK4 (0.64) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL17239118 0.82 IRAK4 (0.58) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL2103513 0.82 IRAK4 (1.00) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL16674268 0.82 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2
Bicarbonate SCHEMBL21811920 0.82 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL2094687 0.82 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2
SCHEMBL10763308 0.82 IRAK4 (0.68) IRAK4ALDH1A1ACHEIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790190-A Curing agent for silicone rubber material 硝基化学阿绍有限公司 2019-05-21 CN claimed
CN-109790190-A Curing agent for silicone rubber material 硝基化学阿绍有限公司 2019-05-21 CN disclosed