Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608219 | 0.83 | CYP3A4 (0.44) | HPGDALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL4444933 | 0.79 | HPGD (1.00) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL6611172 | 0.77 | MAPT (0.57) | HPGDALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL5703500 | 0.76 | HPGD (0.73) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL10469452 | 0.75 | TSHR (0.48) | NPC1RAB9A | |
| SCHEMBL27523461 | 0.75 | HPGD (0.79) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL72112 | 0.74 | HPGD (0.85) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL6605604 | 0.74 | CYP2C19 (0.48) | HPGDALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL3563895 | 0.74 | HPGD (0.47) | HPGDALDH1A1MAPTL3MBTL1MLYCD | |
| SCHEMBL6609151 | 0.73 | HDAC2 (0.47) | HPGDMAPTSMN1; SMN2HDAC6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |