Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103513 | 0.85 | IRAK4 (1.00) | IRAK4HTTCTNNB1MAPTKMT2A | |
| SCHEMBL11768273 | 0.84 | IRAK4 (0.77) | IRAK4HTTCTNNB1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL7846994 | 0.84 | IRAK4 (0.96) | IRAK4HTTCTNNB1MAPTKMT2A | |
| SCHEMBL5887079 | 0.84 | IRAK4 (0.77) | IRAK4HTTCTNNB1MAPTKMT2A | |
| SCHEMBL28124500 | 0.82 | IRAK4 (0.74) | IRAK4HTTCTNNB1MAPTKMT2A | |
| SCHEMBL10407490 | 0.82 | IRAK4 (0.74) | IRAK4HTTCTNNB1MAPTKMT2A | |
| SCHEMBL29639496 | 0.79 | IRAK4 (0.70) | IRAK4HTTCTNNB1MAPTKMT2A | |
| SCHEMBL28306143 | 0.79 | IRAK4 (0.70) | IRAK4HTTCTNNB1MAPTKMT2A | |
| SCHEMBL22579000 | 0.79 | IRAK4 (0.70) | IRAK4HTTCTNNB1MAPTKMT2A | |
| SCHEMBL7013163 | 0.79 | IRAK4 (0.70) | IRAK4HTTCTNNB1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109743875-A | The inhibitor of MENIN-MLL interaction | 生命医药公司 | 2019-05-10 | — | — | CN | disclosed |