⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2590771 | 0.79 | — | — | |
| SCHEMBL794428 | 0.65 | — | — | |
| SCHEMBL16485878 | 0.55 | — | — | |
| SCHEMBL2454966 | 0.49 | — | — | |
| SCHEMBL5407081 | 0.48 | — | — | |
| SCHEMBL21903241 | 0.43 | — | — | |
| SCHEMBL25204735 | 0.42 | — | — | |
| SCHEMBL21722216 | 0.42 | — | — | |
| SCHEMBL21590148 | 0.42 | — | — | |
| SCHEMBL893 | 0.42 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109897-A1 | MODULATORS OF FPR1 AND METHODS OF USING THE SAME | BIOFRONT THERAPEUTICS (BEIJING) CO., LTD. (CN) | 2024-04-04 | — | — | US | claimed |
| EP-3601284-B1 | NAPHTHYRIDINES AS INHIBITORS OF HPK1 | HOFFMANN LA ROCHE (CH) | 2023-12-27 | — | — | EP | claimed |
| CN-117157296-A | Modulators of FPR1 and methods of use thereof | 首都医科大学附属北京天坛医院 | 2023-12-01 | — | — | CN | claimed |
| US-11603373-B2 | TDO2 and IDO1 inhibitors | GENENTECH, INC. (US) | 2023-03-14 | — | — | US | claimed |
| US-11566028-B2 | Bicyclic heterocycles as FGFR inhibitors | INCYTE CORPORATION (US) | 2023-01-31 | — | — | US | claimed |
| EP-3601259-B1 | ISOQUINOLINES AS INHIBITORS OF HPK1 | HOFFMANN LA ROCHE (CH) | 2022-02-23 | — | — | EP | claimed |
| US-20210292281-A1 | PYRAZOLE AND IMIDAZOLE COMPOUNDS FOR INHIBITION OF IL-17 AND RORGAMMA | REATA PHARMACEUTICALS, INC. (US) | 2021-09-23 | — | — | US | claimed |
| WO-2021094209-A1 | SUBSTITUTED PYRROLO TRIAZINE CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN EP3 RECEPTOR ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | WO | claimed |
| US-20210115053-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION | 2021-04-22 | — | — | US | claimed |
| WO-2021076728-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION (US) | 2021-04-22 | — | — | WO | claimed |
| US-7497878-B2 | Azo dyes containing a sulphonamide or amide function for the dyeing of human keratin fibers and method of dyeing and dyeing compositions containing them | L'OREAL, S.A. (FR) | 2009-03-03 | — | — | US | claimed |
| WO-2009001132-A1 | PYRAZINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF LUNG DISEASES | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | claimed |
| WO-2008043788-A2 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-04-17 | — | — | WO | claimed |
| EP-1828183-A1 | 4- (4- (IMIDAZOL-4-YL) PYRIMIDIN-2-YLAMINO) BENZAMIDES AS CDK INHIBITORS | AstraZeneca AB (SE) | 2007-09-05 | — | — | EP | claimed |
| US-20070011830-A1 | Azo dyes containing a sulphonamide or amide function for the dyeing of human keratin fibers and method of dyeing and dyeing compositions containing them | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | claimed |
| EP-1738746-A2 | Use of azo dyes containing a sulphonamide or amide function for the dyeing of human keratin fibres and method of dyeing and dyeing composition containing them | L'OREAL (FR) | 2007-01-03 | — | — | EP | claimed |
| WO-2006064251-A1 | 4- (4- (IMIDAZOL-4-YL) PYRIMIDIN-2-YLAMINO) BENZAMIDES AS CDK INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | claimed |
| EP-0224178-B1 | 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7(1-PIPERAZINYL)-3-QUINOLINE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM | BAYER AG (DE) | 1990-08-01 | — | — | EP | claimed |
| US-4806539-A | 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acids and antibacterial agents containing them | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | claimed |
| EP-0224178-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)-3-quinoline-carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1987-06-03 | — | — | EP | claimed |