Diphenylmethane

Diphenylmethane

SCHEMBL28294258

C=CC(=O)OCCCC.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.67
HPGD P15428 1/20 0.67
THRB P10828 4/20 0.53
ALDH1A1 P00352 4/20 0.51
CYP3A4 P08684 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MAPK1 P28482 2/20 0.51
ATM Q13315 1/20 0.47
HCAR2 Q8TDS4 1/20 0.46
THRA P10827 1/20 0.45
TP53 P04637 1/20 0.44
HSD17B10 Q99714 1/20 0.43
LTA4H P09960 4/20 0.43
LMNA P02545 1/20 0.43
CTSK P43235 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL25297827 0.87 TSHR (0.88) TSHRHPGDTHRBALDH1A1CYP3A4
Toluene SCHEMBL8766954 0.86 TSHR (0.69) TSHRHPGDTHRBALDH1A1CYP3A4
Phenol SCHEMBL28445734 0.86 TSHR (0.69) TSHRHPGDTHRBALDH1A1CYP3A4
Iodobenzene SCHEMBL28922112 0.86 TSHR (0.69) TSHRHPGDTHRBALDH1A1CYP3A4
Phenol SCHEMBL7901401 0.86 TSHR (0.69) TSHRHPGDTHRBALDH1A1CYP3A4
Benzene SCHEMBL28232511 0.85 TSHR (0.85) TSHRHPGDTHRBALDH1A1CYP3A4
Phthalic Acid SCHEMBL9652344 0.85 TSHR (0.67) TSHRHPGDTHRBALDH1A1CYP3A4
Styrene SCHEMBL3196230 0.85 TSHR (0.67) TSHRHPGDTHRBALDH1A1CYP3A4
Styrene SCHEMBL67823 0.85 TSHR (0.67) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL13372762 0.85 TSHR (0.67) TSHRHPGDTHRBALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109836797-A A kind of modified polyalcohol resin composite materials and preparation method thereof 李娜 2019-06-04 CN disclosed
CN-109777124-A A kind of modification dimethyl carbonate lotion of hydrolysis and preparation method thereof 戴�峰 2019-05-21 CN disclosed