Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 5/20 | 0.45 |
| ▸ | METAP2 | P50579 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2268059 | 0.98 | CHEK1 (1.00) | CHEK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29589219 | 0.98 | CHEK1 (1.00) | CHEK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1273919 | 0.83 | CHEK1 (0.73) | CHEK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL28642996 | 0.81 | CHEK1 (0.70) | CHEK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1273798 | 0.81 | CHEK1 (0.70) | CHEK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL28858305 | 0.81 | CHEK1 (0.70) | CHEK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14389670 | 0.81 | CHEK1 (0.70) | CHEK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL2568456 | 0.81 | CHEK1 (0.70) | CHEK1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29536144 | 0.81 | CHEK1 (0.70) | CHEK1KDM4EMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL15640013 | 0.81 | CHEK1 (0.70) | CHEK1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761986-A | Three simultaneously ring analog derivative inhibitor, preparation method and applications | 上海翰森生物医药科技有限公司 | 2019-05-17 | — | — | CN | disclosed |