Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27386816 | 0.96 | TDP1 (0.42) | TDP1TSHRL3MBTL1ALDH1A1PPARG | |
| SCHEMBL24592261 | 0.93 | TDP1 (0.41) | TDP1TSHRL3MBTL1ALDH1A1PPARG | |
| SCHEMBL16996644 | 0.86 | TDP1 (0.49) | TDP1TSHRL3MBTL1ALDH1A1PPARG | |
| SCHEMBL8862687 | 0.86 | TDP1 (0.49) | TDP1TSHRL3MBTL1ALDH1A1PPARG | |
| SCHEMBL22112059 | 0.83 | TSHR (0.37) | TDP1TSHRL3MBTL1ALDH1A1POLB | |
| SCHEMBL17435832 | 0.82 | TDP1 (0.46) | TDP1TSHRL3MBTL1ALDH1A1PPARG | |
| SCHEMBL19418927 | 0.82 | TDP1 (0.46) | TDP1TSHRL3MBTL1ALDH1A1PPARG | |
| SCHEMBL13531178 | 0.82 | TDP1 (0.46) | TDP1TSHRL3MBTL1ALDH1A1PPARG | |
| SCHEMBL22489508 | 0.81 | TLR2 (0.38) | TDP1TSHRL3MBTL1ALDH1A1PPARG | |
| SCHEMBL23157471 | 0.81 | TLR2 (0.38) | TDP1TSHRL3MBTL1ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651286-B | High-selectivity synthesis method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-109651286-A | A kind of highly selective 4-(4- aminophenyl) morpholine -3- ketone synthetic method | 新发药业有限公司 | 2019-04-19 | — | — | CN | disclosed |