SCHEMBL28294717

SCHEMBL28294717

COS(=O)(=O)O.Cc1nccc2ccccc12

nearest known ligand 0.70

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.70
PLAU P00749 2/20 0.42
F12 P00748 1/20 0.42
NCF1 P14598 1/20 0.42
NOS3 P29474 1/20 0.42
NOS1 P29475 1/20 0.42
NOS2 P35228 1/20 0.42
BACE1 P56817 1/20 0.42
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
PLG P00747 1/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL27870095 0.90 CYP2A6 (0.81) CYP2A6PLAUF12NCF1NOS3
Sulfuric Acid SCHEMBL27870093 0.90 CYP2A6 (0.81) CYP2A6PLAUF12NCF1NOS3
SCHEMBL70488 0.84 CYP2A6 (1.00) CYP2A6PLAUF12NCF1NOS3
Hydrochloric Acid SCHEMBL29827768 0.82 CYP2A6 (0.95) CYP2A6PLAUF12NCF1NOS3
Hydrochloric Acid SCHEMBL2830989 0.82 CYP2A6 (0.95) CYP2A6PLAUF12NCF1NOS3
Iodide SCHEMBL27536286 0.82 CYP2A6 (0.95) CYP2A6PLAUF12NCF1NOS3
Formic Acid SCHEMBL28681087 0.81 CYP2A6 (0.78) CYP2A6PLAUF12NCF1NOS3
SCHEMBL28264878 0.80 CYP2A6 (0.64) CYP2A6CYP3A4TSHRCYP2C19ALDH1A1
SCHEMBL27891679 0.77 CYP2A6 (0.84) CYP2A6PLAUF12NCF1NOS3
SCHEMBL3659595 0.75 MAPT (0.48) RAB9AMAPTSMN1; SMN2KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109643817-A Use of ionic liquids as adjuvants in electrochemistry 雷恩第大学 2019-04-16 CN disclosed