Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL17238894 | 0.92 | HDAC8 (0.43) | HDAC8APOBEC3AAPOBEC3GKDM4ESMN1; SMN2 | |
| SCHEMBL2699540 | 0.87 | HDAC8 (0.43) | HDAC8APOBEC3AAPOBEC3GKDM4ESMN1; SMN2 | |
| SCHEMBL329129 | 0.85 | — | — | |
| SCHEMBL27686412 | 0.85 | APOBEC3A (0.43) | HDAC8APOBEC3AAPOBEC3GKDM4ESMN1; SMN2 | |
| Fluoride Ion SCHEMBL1896291 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL1996433 | 0.83 | — | — | |
| Water SCHEMBL3793832 | 0.83 | — | — | |
| Sulfuric Acid SCHEMBL2866335 | 0.82 | HDAC8 (0.42) | HDAC8APOBEC3AAPOBEC3GKDM4ESMN1; SMN2 | |
| Sulfuric Acid SCHEMBL2866328 | 0.82 | HDAC8 (0.45) | HDAC8APOBEC3AAPOBEC3GKDM4ESMN1; SMN2 | |
| Fluoride Ion SCHEMBL27602339 | 0.81 | HDAC8 (0.52) | HDAC8APOBEC3AAPOBEC3GKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111836849-B | Process for producing fibers, films and moldings of polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-3512905-B1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2022-08-24 | — | — | EP | disclosed |
| CN-109790292-B | Process for preparing polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-111836849-A | Process for producing fibers, films and moldings of polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-109790292-A | Process for preparing polybenzazole polymer (P) | 巴斯夫欧洲公司 | 2019-05-21 | — | — | CN | disclosed |