Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.80 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.80 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 7/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256770 | 0.94 | PRSS1 (0.89) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL3221063 | 0.93 | PRSS1 (0.86) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL30863762 | 0.93 | PRSS1 (0.86) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL28270019 | 0.92 | PRSS1 (0.84) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL30849898 | 0.92 | PRSS1 (0.84) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL28205289 | 0.90 | PRSS1 (0.92) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL434343 | 0.90 | PRSS1 (0.81) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL29439073 | 0.90 | PRSS1 (0.81) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL3680561 | 0.90 | PRSS1 (0.72) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL9620202 | 0.90 | PRSS1 (0.72) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641873-A | N- (pyridine -2- base) pyridine-sulfamide derivative and its purposes for disease treatment | 诺华股份有限公司 | 2019-04-16 | — | — | CN | disclosed |