SCHEMBL28295928

SCHEMBL28295928

CCCCCC(O)(C(=O)OC)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.51
GAA P10253 1/20 0.49
SCN5A Q14524 3/20 0.48
SCN9A Q15858 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SRC P12931 1/20 0.44
SIGMAR1 Q99720 1/20 0.43
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
NAAA Q02083 1/20 0.41
NR1H2 P55055 2/20 0.40
NR1H3 Q13133 2/20 0.40
MBOAT4 Q96T53 1/20 0.40
PRSS1 P07477 1/20 0.40
CTSG P08311 1/20 0.40
CTRB1 P17538 1/20 0.40
CMA1 P23946 1/20 0.40
KIF11 P52732 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28551396 0.98 SCN5A (0.50) KCNN4GAASCN5ASCN9AL3MBTL1
SCHEMBL11329310 0.88 KCNN4 (0.56) KCNN4GAAL3MBTL1KMT2ATDP1
SCHEMBL20850649 0.84 KCNN4 (0.49) KCNN4SCN5ASCN9AKMT2ASRC
SCHEMBL27554525 0.83 TSHR (0.53) GAASCN5ASCN9AL3MBTL1KMT2A
SCHEMBL29140992 0.83 TSHR (0.53) GAASCN5ASCN9AL3MBTL1KMT2A
SCHEMBL27528841 0.83 SCN5A (0.48) GAASCN5ASCN9AKMT2ASIGMAR1
SCHEMBL11835995 0.83 SCN5A (0.56) GAASCN5ASCN9ASIGMAR1NAAA
SCHEMBL1275973 0.83 SCN5A (0.52) GAASCN5ASCN9AL3MBTL1KMT2A
SCHEMBL11831207 0.83 SCN5A (0.56) GAASCN5ASCN9ASIGMAR1NAAA
SCHEMBL8669195 0.81 SCN5A (0.55) GAASCN5ASCN9ASIGMAR1NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810059-A A kind of preparation method of left-handed hydrochloric acid demethyl benzene ring pelargonate 盘锦格林凯默科技有限公司 2019-05-28 CN claimed