Ethylene Glycol

Ethylene Glycol

SCHEMBL28296153

C=CC(=O)OC(C)=O.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.48
ALDH1A1 P00352 7/20 0.41
HSD17B10 Q99714 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HPGD P15428 1/20 0.39
THRB P10828 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL475313 0.90
SCHEMBL21954820 0.87
SCHEMBL3273152 0.87
SCHEMBL1148750 0.87
Ethylene SCHEMBL27514669 0.87 TSHR (0.47) TSHRALDH1A1HSD17B10TDP1TP53
Butyl Alcohol SCHEMBL28956811 0.86 TSHR (0.50) TSHRALDH1A1HSD17B10TDP1TP53
Acetic Acid SCHEMBL28611836 0.85 TSHR (0.45) TSHRALDH1A1HSD17B10TDP1TP53
Ethylene Glycol SCHEMBL27849780 0.85 TSHR (0.56) TSHRALDH1A1HSD17B10TDP1TP53
Propene SCHEMBL28423031 0.83 TSHR (0.43) TSHRALDH1A1HSD17B10TDP1TP53
Propylene Glycol SCHEMBL5797912 0.83 TSHR (0.44) TSHRALDH1A1HSD17B10TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116693896-A Preparation method and application of nanogel capable of intelligently regulating and controlling crosslinking density 中国药科大学 2023-09-05 CN disclosed
CN-109804118-A Paper with waterproof and part heat sealability 托普希姆股份有限公司 2019-05-24 CN disclosed