Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.48 |
| ▸ | CLK1 | P49759 | 2/20 | 0.48 |
| ▸ | CLK2 | P49760 | 2/20 | 0.48 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30362451 | 0.83 | CASR (0.46) | CLK4DYRK1ADYRK1BCLK1CLK2 | |
| SCHEMBL19878225 | 0.83 | CASR (0.46) | CLK4DYRK1ADYRK1BCLK1CLK2 | |
| SCHEMBL30362764 | 0.82 | CLK4 (0.44) | CLK4DYRK1ADYRK1BCLK1CLK2 | |
| SCHEMBL19878451 | 0.82 | CLK4 (0.44) | CLK4DYRK1ADYRK1BCLK1CLK2 | |
| SCHEMBL5823848 | 0.79 | APP (0.60) | CLK4DYRK1ADYRK1BCLK1CLK2 | |
| SCHEMBL5494839 | 0.73 | FGFR1 (0.52) | CLK4ACP1ABL1USP2ALDH1A1 | |
| SCHEMBL29498169 | 0.72 | RIPK2 (0.65) | ABL1 | |
| SCHEMBL18571985 | 0.70 | MEN1 (0.52) | CLK4DYRK1ADYRK1BCLK1CLK2 | |
| SCHEMBL29911298 | 0.70 | MEN1 (0.52) | CLK4DYRK1ADYRK1BCLK1CLK2 | |
| SCHEMBL2805624 | 0.69 | FGFR1 (0.44) | CLK4DYRK1ADYRK1BCLK1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843858-A | Certain chemical entities, composition and method | 润新生物公司 | 2019-06-04 | — | — | CN | disclosed |