Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17886845 | 0.91 | CYP19A1 (0.41) | CYP19A1MAPTCHRM3APOBEC3AAPOBEC3G | |
| SCHEMBL685924 | 0.83 | CYP19A1 (0.35) | CYP19A1MAPTCHRM3APOBEC3AAPOBEC3G | |
| SCHEMBL995834 | 0.83 | CYP19A1 (0.40) | CYP19A1MAPTCHRM3APOBEC3AAPOBEC3G | |
| SCHEMBL995833 | 0.83 | CYP19A1 (0.40) | CYP19A1MAPTCHRM3APOBEC3AAPOBEC3G | |
| SCHEMBL13811600 | 0.83 | CYP19A1 (0.40) | CYP19A1MAPTCHRM3APOBEC3AAPOBEC3G | |
| SCHEMBL13073268 | 0.82 | CYP19A1 (0.46) | CYP19A1CHRM3APOBEC3AAPOBEC3GHTT | |
| SCHEMBL1682649 | 0.82 | CYP19A1 (0.50) | CYP19A1CHRM3HTTSMN1; SMN2CHRM2 | |
| SCHEMBL3678287 | 0.81 | CYP19A1 (0.36) | CYP19A1MAPTCHRM3APOBEC3AAPOBEC3G | |
| SCHEMBL3676448 | 0.81 | CYP19A1 (0.36) | CYP19A1MAPTCHRM3APOBEC3AAPOBEC3G | |
| SCHEMBL9050652 | 0.81 | MAPT (0.50) | CYP19A1MAPTCHRM3APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824516-A | A kind of preparation method of trans- -4- hydroxyl thiacyclohexane t-butyl formate | 泰州精英化成医药科技有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-115947704-B | Preparation method of organic luminescent material intermediate 1-bromodibenzofuran | 武汉理工大学深圳研究院 | 2024-04-09 | — | — | CN | disclosed |
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-115947704-A | Preparation method of organic luminescent material intermediate 1-bromodibenzofuran | 武汉理工大学深圳研究院 | 2023-04-11 | — | — | CN | disclosed |
| CN-109824516-A | A kind of preparation method of trans- -4- hydroxyl thiacyclohexane t-butyl formate | 泰州精英化成医药科技有限公司 | 2019-05-31 | — | — | CN | disclosed |