Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.83 |
| ▸ | TLR2 | O60603 | 1/20 | 0.83 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.83 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.83 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL9276378 | 1.00 | ERN1 (0.83) | ERN1TLR2TLR1TLR6CA12 | |
| Ethylenediamine SCHEMBL28149520 | 0.98 | ERN1 (0.81) | ERN1TLR2TLR1TLR6CA12 | |
| Ethylenediamine SCHEMBL28650216 | 0.98 | ERN1 (0.81) | ERN1TLR2TLR1TLR6CA12 | |
| Methylamine SCHEMBL28936774 | 0.91 | ERN1 (0.93) | ERN1TLR2TLR1TLR6CA12 | |
| SCHEMBL30485148 | 0.91 | ERN1 (1.00) | ERN1TLR2TLR1TLR6CA12 | |
| SCHEMBL929734 | 0.91 | ERN1 (1.00) | ERN1TLR2TLR1TLR6CA12 | |
| SCHEMBL16004 | 0.91 | ERN1 (1.00) | ERN1TLR2TLR1TLR6CA12 | |
| SCHEMBL28657715 | 0.91 | ERN1 (0.73) | ERN1TLR2TLR1TLR6CA12 | |
| SCHEMBL4450612 | 0.90 | ERN1 (0.96) | ERN1TLR2TLR1TLR6CA12 | |
| SCHEMBL11407272 | 0.90 | ERN1 (0.96) | ERN1TLR2TLR1TLR6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116782516-B | Universal process for preparing copper printed circuit based on homogeneous ion type catalytic ink | 南华大学 | 2024-01-23 | — | — | CN | claimed |
| CN-116782516-A | Universal process for preparing copper printed circuit based on homogeneous ion type catalytic ink | 南华大学 | 2023-09-19 | — | — | CN | claimed |
| CN-109836354-A | A kind of terbium coordination compound and its synthetic method containing O-VANILLIN contracting ethylenediamine | 天津工业大学 | 2019-06-04 | — | — | CN | claimed |
| CN-116782516-B | Universal process for preparing copper printed circuit based on homogeneous ion type catalytic ink | 南华大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-116782516-A | Universal process for preparing copper printed circuit based on homogeneous ion type catalytic ink | 南华大学 | 2023-09-19 | — | — | CN | disclosed |