SCHEMBL28296492

SCHEMBL28296492

NCc1cc(C2(c3ccc(N)c(CN)c3)c3ccccc3-c3ccccc32)ccc1N

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
MAPT P10636 1/20 0.53
OPRK1 P41145 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
POLB P06746 2/20 0.35
DPP4 P27487 2/20 0.35
PDK2 Q15119 2/20 0.32
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PNMT P11086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580422 0.85 MAPT (0.51) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL7052838 0.85 MAPT (0.51) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL28026138 0.82 ESR1 (0.59) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL6138389 0.80 MEN1 (0.62) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL30952102 0.80 MEN1 (0.62) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL21010879 0.78 ESR1 (0.44) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL5968601 0.76 MEN1 (0.56) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL283244 0.76 ESR1 (0.65) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL30977274 0.76 MEN1 (0.56) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL2405956 0.76 MEN1 (0.56) MEN1KMT2AKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110092936-A Optical laminate 住友化学株式会社 2019-08-06 CN disclosed
CN-109796761-A Display screen component, preparation method and display terminal 努比亚技术有限公司 2019-05-24 CN disclosed