Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601517 | 0.86 | KDM4E (0.43) | KDM4EPOLBHCAR2MEN1KMT2A | |
| SCHEMBL29207918 | 0.82 | KDM4E (0.40) | KDM4EPOLBHCAR2MEN1KMT2A | |
| Formic Acid SCHEMBL31186859 | 0.78 | POLB (0.52) | KDM4EPOLBHCAR2MEN1KMT2A | |
| SCHEMBL4974 | 0.77 | — | — | |
| SCHEMBL28508474 | 0.74 | POLB (0.50) | KDM4EPOLBHCAR2MEN1KMT2A | |
| SCHEMBL28049807 | 0.72 | CYP2A6 (0.47) | MEN1KMT2AALOX15ALDH1A1MAPK1 | |
| Formamide SCHEMBL28851288 | 0.71 | KMT2A (0.41) | KDM4EPOLBHCAR2MEN1KMT2A | |
| SCHEMBL30639735 | 0.70 | — | — | |
| SCHEMBL13653714 | 0.70 | — | — | |
| SCHEMBL102060 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108774220-B | For treating compound and its application of myocardial ischemia | 西安培华学院 | 2019-04-23 | — | — | CN | disclosed |