Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL11345463 | 0.88 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL28506647 | 0.88 | FFAR3 (0.56) | FFAR3ALDH1A1LMNAHSD11B1EPHX1 | |
| SCHEMBL28868682 | 0.81 | TDP1 (0.62) | FFAR3ALDH1A1TDP1CHRNB2CHRNB4 | |
| Propionic Acid SCHEMBL25249434 | 0.79 | FFAR3 (0.83) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL16335350 | 0.79 | — | — | |
| Propionic Acid SCHEMBL29094849 | 0.79 | FFAR3 (0.83) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Cyclopentane SCHEMBL28987168 | 0.79 | FFAR3 (0.83) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Cyclopentane SCHEMBL97373 | 0.79 | FFAR3 (0.83) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Cyclohexane SCHEMBL2585876 | 0.79 | FFAR3 (0.83) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL5062880 | 0.79 | FFAR3 (0.83) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267948-A | Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and methods of making the modulators | 弗特克斯药品有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110088096-A | Piperidine derivatives as inhibitors of ubiquitin-specific protease 7 | 阿尔麦克探索有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-109803962-A | Modulators of cystic fibrosis transmembrane conductance regulator proteins, pharmaceutical compositions, methods of treatment, and methods for making the modulators | 弗特克斯药品有限公司 | 2019-05-24 | — | — | CN | disclosed |