⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445540 | 1.00 | — | — | |
| SCHEMBL3180256 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL29056655 | 0.98 | CYP1A2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL6778419 | 0.98 | CYP1A2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL29056653 | 0.98 | CYP1A2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL2673742 | 0.98 | CYP1A2 (0.52) | — | |
| SCHEMBL1489649 | 0.93 | CYP1A2 (0.62) | — | |
| SCHEMBL7207815 | 0.89 | CYP1A2 (0.62) | — | |
| SCHEMBL1375288 | 0.87 | CYP1A2 (0.50) | — | |
| SCHEMBL1966053 | 0.87 | CYP1A2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148879-A1 | QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF ACKR3 | STICHTING VU (NL) | 2022-07-14 | — | — | WO | disclosed |
| US-20220122691-A1 | HtrA Inhibitors and CagA Inhibitors and Use Thereof | Psomagen Inc. (US) | 2022-04-21 | — | — | US | disclosed |
| EP-3277682-B1 | 6-MORPHOLINYL-2-PYRAZOLYL-9H-PURINE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | DAIICHI SANKYO CO LTD (JP) | 2019-04-24 | — | — | EP | disclosed |
| US-10174035-B2 | 6-morpholinyl-2-pyrazolyl-9H-purine derivatives and their use as PI3K inhibitors | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-01-08 | — | — | US | disclosed |
| US-20180072732-A1 | 6-MORPHOLINYL-2-PYRAZOLYL-9H-PURINE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-03-15 | — | — | US | disclosed |
| US-20180072732-A1 | 6-MORPHOLINYL-2-PYRAZOLYL-9H-PURINE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-03-15 | — | — | US | disclosed |
| WO-2016157074-A1 | 6-MORPHOLINYL-2-PYRAZOLYL-9H-PURINE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-10-06 | — | — | WO | disclosed |
| US-8273736-B2 | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LABORATORIES (US) | 2012-09-25 | — | — | US | disclosed |
| EP-2394998-A1 | 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010069504-A1 | (3-OXO)PYRIDIN-4-YLUREA DERIVATIVES AS PDE4 INHIBITORS | ALMIRALL, S.A. (ES) | 2010-06-24 | — | — | WO | disclosed |
| US-6949553-B2 | Aliphatic compounds, their synthesis method, and utilization of the same | MARUHA CORPORATION (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20050043347-A1 | Thienopyridine and furopyridine kinase inhibitors | ABBVIE INC. | 2005-02-24 | — | — | US | disclosed |
| WO-2005010009-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2005-02-03 | — | — | WO | disclosed |
| US-20050026944-A1 | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LABORATORIES | 2005-02-03 | — | — | US | disclosed |
| US-20050020619-A1 | Thienopyridine kinase inhibitors | ABBOTT LABORATORIES | 2005-01-27 | — | — | US | disclosed |
| US-20040162435-A1 | Novel aliphatic compound, method of synthesis, and method of utilization | MARUHA NICHIRO SEAFOODS, INC. (JP) | 2004-08-19 | — | — | US | disclosed |
| EP-1408030-A1 | NOVEL ALIPHATIC COMPOUND, METHOD OF SYNTHESIS, AND METHOD OF UTILIZATION | Maruha Corporation (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-20040039044-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | RUI YUANJIN (US) | 2004-02-26 | — | — | US | disclosed |
| EP-1339677-A1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | Warner-Lambert Company LLC (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002036560-A1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-10 | — | — | WO | disclosed |