Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616451 | 0.90 | MAPT (0.46) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4983413 | 0.83 | MAPT (0.48) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL181942 | 0.83 | MAPT (0.48) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL418090 | 0.83 | — | — | |
| SCHEMBL28217512 | 0.81 | — | — | |
| SCHEMBL15796374 | 0.81 | MAPT (0.47) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7629307 | 0.79 | — | — | |
| SCHEMBL2325591 | 0.79 | — | — | |
| SCHEMBL20734518 | 0.79 | — | — | |
| SCHEMBL13994295 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734959-A | A kind of heat-resistance type radical initiator and its preparation method and application | 清远市普塞呋磷化学有限公司 | 2019-05-10 | — | — | CN | disclosed |