Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29739401 | 1.00 | KMT2A (0.47) | KMT2AMEN1POLBRAB9ANPSR1 | |
| SCHEMBL29739584 | 0.80 | SMN1; SMN2 (0.40) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL29739303 | 0.79 | POLB (0.46) | KMT2AMEN1POLBRAB9ANPSR1 | |
| SCHEMBL26633326 | 0.79 | POLB (0.46) | KMT2AMEN1POLBRAB9ANPSR1 | |
| SCHEMBL16672098 | 0.78 | KMT2A (0.58) | KMT2AMEN1POLBRAB9ANPSR1 | |
| SCHEMBL3475291 | 0.77 | SLC2A1 (0.42) | KMT2AMEN1RAB9ANPSR1NPC1 | |
| SCHEMBL29444257 | 0.77 | POLB (0.63) | KMT2AMEN1POLBRAB9ANPSR1 | |
| SCHEMBL2488923 | 0.77 | POLB (0.63) | KMT2AMEN1POLBRAB9ANPSR1 | |
| SCHEMBL17868230 | 0.77 | POLB (0.67) | KMT2AMEN1POLBRAB9ANPSR1 | |
| SCHEMBL22069015 | 0.77 | NPC1 (0.52) | KMT2AMEN1POLBRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843892-B | Oxadiazepinone derivatives and their use in the treatment of hepatitis B infections | 诺维拉治疗公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-109843892-A | Dislike diazepine ketone derivatives and its purposes in treatment hepatitis B infection | 诺维拉治疗公司 | 2019-06-04 | — | — | CN | disclosed |