Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27742737 | 0.87 | TDP1 (0.39) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28039170 | 0.84 | TDP1 (0.39) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28325943 | 0.83 | TDP1 (0.36) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27830226 | 0.82 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28115246 | 0.82 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28114837 | 0.80 | TDP1 (0.36) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28309890 | 0.78 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28755149 | 0.72 | TACR1 (0.30) | — | |
| Tert-Butyl Formate SCHEMBL28828203 | 0.72 | TDP1 (0.52) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28331255 | 0.71 | TDP1 (0.68) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104974161-B | The analog of 4H- pyrazolo [1,5- α] benzimidazole compound as PARP inhibitor | Hubei company limited of Bio-pharmaceutical Industry Institute for Research and Technology (CN) | 2019-11-01 | — | — | CN | disclosed |
| CN-106459057-B | Analogs of 4H-pyrazolo [1,5- α ] benzimidazole compounds as PARP inhibitors | 湖北生物医药产业技术研究院有限公司 | 2019-06-07 | — | — | CN | disclosed |