Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31577547 | 0.82 | LOX (0.40) | LOXMBOAT4ALDH1A1MEN1KMT2A | |
| SCHEMBL2561780 | 0.82 | LOX (0.40) | LOXMBOAT4ALDH1A1MEN1KMT2A | |
| SCHEMBL27827228 | 0.79 | LOX (0.41) | LOXMBOAT4 | |
| SCHEMBL5547208 | 0.79 | LOX (0.51) | LOXMBOAT4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3465642 | 0.77 | LOX (0.39) | LOXMBOAT4 | |
| SCHEMBL1404067 | 0.74 | LOX (0.41) | LOXMBOAT4ALDH1A1HPGDGRM5 | |
| SCHEMBL28242120 | 0.74 | LOX (0.41) | LOXMBOAT4ALDH1A1HPGD | |
| SCHEMBL30253017 | 0.74 | LOX (0.41) | LOXMBOAT4ALDH1A1HPGDGRM5 | |
| SCHEMBL3465576 | 0.72 | LOX (0.39) | LOXMBOAT4 | |
| SCHEMBL12084074 | 0.71 | CCR1 (0.46) | LOXMBOAT4ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843891-A | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2019-06-04 | — | — | CN | disclosed |