Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299572 | 0.90 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28299846 | 0.90 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28299571 | 0.88 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28028894 | 0.87 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28298248 | 0.87 | PIK3CD (0.46) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28298220 | 0.83 | PIK3CD (0.52) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28298209 | 0.83 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28299574 | 0.83 | PIK3CD (0.58) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28299551 | 0.82 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 | |
| SCHEMBL28299568 | 0.81 | PIK3CD (0.50) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |