SCHEMBL28298417

SCHEMBL28298417

C=CCOC(=O)C(CCCCC)OCC

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ZDHHC7 Q9NXF8 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 1/20 0.34
GPR84 Q9NQS5 3/20 0.33
MAPT P10636 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
PLA2G2C Q5R387 1/20 0.33
FFAR1 O14842 1/20 0.33
CA1 P00915 1/20 0.33
LTA4H P09960 1/20 0.33
ABCB1 P08183 1/20 0.33
FAAH O00519 2/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28790714 0.88 TSHR (0.51) TSHRZDHHC7TDP1HPGDGPR84
SCHEMBL28791527 0.88 TSHR (0.51) TSHRZDHHC7TDP1HPGDGPR84
SCHEMBL27579880 0.82 TDP1 (0.47) TSHRTDP1MAPTCYP3A4CYP2C9
SCHEMBL27598398 0.81 ZDHHC7 (0.46) ZDHHC7GPR84MAPTFFAR1FAAH
SCHEMBL11723542 0.81 ZDHHC7 (0.46) ZDHHC7GPR84MAPTFFAR1FAAH
SCHEMBL27468110 0.81 TSHR (0.41) TSHRTDP1ALDH1A1MAPTCYP3A4
SCHEMBL28663773 0.80 TSHR (0.56) TSHRZDHHC7TDP1HPGDALDH1A1
SCHEMBL27595252 0.80 TSHR (0.43) TSHRTDP1ALDH1A1MAPTCYP3A4
SCHEMBL5403623 0.79 TSHR (0.49) TSHRZDHHC7GPR84MAPTCYP3A4
SCHEMBL22345906 0.79 TSHR (0.65) TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710283-B Cyclopentanol compound 国际香料和香精公司 2019-06-11 CN disclosed