Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.51 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10756940 | 0.76 | BRD4 (0.70) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28296842 | 0.72 | NPC1 (0.37) | — | |
| SCHEMBL25746011 | 0.71 | BRD4 (0.53) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28288944 | 0.71 | BRD4 (0.49) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24007585 | 0.70 | BRD4 (0.51) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19995938 | 0.70 | MEN1 (0.41) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19996130 | 0.70 | MEN1 (0.41) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19039741 | 0.70 | BRD4 (0.52) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30912528 | 0.69 | BRD4 (0.70) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30912553 | 0.69 | BRD4 (0.70) | BRD4PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715155-A | blood brain barrier-penetrating agent dopamine- β -hydroxylase inhibitors | 巴尔-波特拉及康邦亚股份有限公司 | 2019-05-03 | — | — | CN | disclosed |