Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.79 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.79 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646512 | 0.88 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL14021512 | 0.88 | CYSLTR1 (0.80) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8650454 | 0.86 | CYSLTR1 (0.79) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL10446560 | 0.84 | CYSLTR1 (0.79) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8712492 | 0.84 | CYSLTR1 (0.75) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8834916 | 0.83 | FFAR1 (0.83) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8709593 | 0.82 | FFAR1 (0.81) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL8666314 | 0.82 | CYSLTR1 (0.72) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL9150476 | 0.82 | CYSLTR1 (0.72) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 | |
| SCHEMBL10446852 | 0.81 | CYSLTR1 (0.75) | CYSLTR1CYSLTR2FFAR1AKR1B1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789150-A | It is certain to be used to treat bronchiectasic (2S)-N- [(1S) -1- cyano -2- phenethyl] -1,4- oxazepine cycloheptane -2- formamide | 英斯梅德股份有限公司 | 2019-05-21 | — | — | CN | disclosed |