SCHEMBL28299070

SCHEMBL28299070

CCCCC1CC(C)CCC1=O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.41
CYP1A2 P05177 4/20 0.35
CYP19A1 P11511 11/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2691796 0.82
SCHEMBL7622428 0.81 MEN1 (0.34) TLR4CYP1A2CYP19A1MEN1KMT2A
SCHEMBL9190051 0.80 TLR4 (0.44) TLR4KMT2A
SCHEMBL2690407 0.76 CYP1A2 (0.47) TLR4CYP1A2CYP19A1
SCHEMBL11382008 0.75 TLR4 (0.49) TLR4CYP1A2CYP19A1
SCHEMBL28115082 0.75 TLR4 (0.41) TLR4CYP1A2CYP19A1
SCHEMBL28035595 0.75 TLR4 (0.41) TLR4CYP1A2CYP19A1MEN1KMT2A
SCHEMBL9924737 0.75 TLR4 (0.53) TLR4
SCHEMBL6907551 0.75 TLR4 (0.47) TLR4KMT2A
SCHEMBL1824692 0.75 NPC1 (0.45) TLR4CYP1A2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109704932-A Catalytic hydrogenation prepares 2,6- di-t-butyl -4 methyl cyclohexanol method 中国石油化工股份有限公司 2019-05-03 CN disclosed