Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 8/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28029221 | 0.89 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL28298220 | 0.86 | PIK3CD (0.52) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL28298209 | 0.85 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL28299572 | 0.85 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL28299551 | 0.84 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL300881 | 0.82 | PIK3CD (0.66) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL28298242 | 0.82 | PIK3CD (0.45) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL28299780 | 0.82 | PIK3CD (0.45) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL28299846 | 0.82 | PIK3CD (0.49) | PIK3CDPIK3CBPIK3CGPIK3CAKDM4E | |
| SCHEMBL28299568 | 0.80 | PIK3CD (0.50) | PIK3CDPIK3CBPIK3CGPIK3CACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |