Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298229 | 0.88 | KDM4E (0.44) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL28299737 | 0.85 | KDM4E (0.42) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL28299693 | 0.85 | KDM4E (0.46) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL28298255 | 0.84 | KDM4E (0.43) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL300939 | 0.83 | KDM4E (0.62) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL28298238 | 0.82 | KDM4E (0.42) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL15206762 | 0.79 | PTK2 (0.47) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL28298221 | 0.76 | KDM4E (0.44) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL28299583 | 0.76 | KDM4E (0.55) | KDM4EHPGDALDH1A1GLAGAA | |
| SCHEMBL28298231 | 0.75 | KDM4E (0.54) | KDM4EHPGDALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109846884-A | With TOR kinase inhibitor for treating cancer | 西格诺药品有限公司 | 2019-06-07 | — | — | CN | disclosed |