Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977481 | 0.90 | MAPT (0.67) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL977479 | 0.90 | MAPT (0.67) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL5082312 | 0.84 | MAPT (0.71) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL30383768 | 0.84 | MAPT (0.71) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL5082313 | 0.84 | MAPT (0.71) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| SCHEMBL25193904 | 0.84 | MAPT (0.71) | MAPTNPSR1KMT2AMEN1KCNA3 | |
| Chalcone SCHEMBL27749563 | 0.83 | MAPT (0.63) | MAPTKMT2AMEN1CYP3A4ABCG2 | |
| SCHEMBL19182748 | 0.78 | TDP1 (0.74) | MAPTKMT2AMEN1CYP3A4ATM | |
| SCHEMBL19182750 | 0.78 | TDP1 (0.74) | MAPTKMT2AMEN1CYP3A4ATM | |
| SCHEMBL15631516 | 0.78 | ABCG2 (0.65) | MAPTNPSR1CYP3A4ABCG2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776408-A | A kind of preparation method of 7- hydroxyl -2- quinolinone | 上海医药工业研究院 | 2019-05-21 | — | — | CN | disclosed |