Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998281 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL781659 | 0.79 | CYP1A2 (0.87) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL8675692 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL29577310 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL20719854 | 0.76 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL6708175 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL5795083 | 0.76 | CYP1A2 (1.00) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL12528786 | 0.76 | TDP1 (0.56) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27538332 | 0.75 | CYP1A2 (0.97) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 | |
| SCHEMBL29823784 | 0.74 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110022902-A | Conjugates comprising a GLP-1/glucagon dual agonist, a linker and hyaluronic acid | 赛诺菲 | 2019-07-16 | — | — | CN | disclosed |