SCHEMBL28301989

SCHEMBL28301989

CCCCCC(=O)CCC(C)(C(=O)O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
MAPT P10636 1/20 0.55
AKR1B1 P15121 1/20 0.46
HAO1 Q9UJM8 1/20 0.46
GPR84 Q9NQS5 7/20 0.45
PPARG P37231 7/20 0.45
PPARD Q03181 7/20 0.45
PPARA Q07869 7/20 0.45
HDAC11 Q96DB2 5/20 0.45
TSHR P16473 4/20 0.45
PTPN1 P18031 3/20 0.45
ALDH1A1 P00352 2/20 0.45
TLR2 O60603 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
FABP4 P15090 2/20 0.45
SLC22A6 Q4U2R8 1/20 0.45
SLC22A8 Q8TCC7 1/20 0.45
MEN1 O00255 1/20 0.45
ESR1 P03372 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491385 0.81 KMT2A (0.56) KMT2AMAPTAKR1B1HAO1GPR84
SCHEMBL2241779 0.81 GGPS1 (0.46) KMT2AAKR1B1GPR84PPARGPPARD
SCHEMBL8897711 0.79 KMT2A (0.59) KMT2AMAPTHAO1GPR84PPARG
SCHEMBL8096567 0.79 KMT2A (0.59) KMT2AMAPTHAO1GPR84PPARG
SCHEMBL18085816 0.79 KMT2A (0.59) KMT2AMAPTHAO1GPR84PPARG
SCHEMBL5859353 0.79 GGPS1 (0.50) KMT2AGPR84PPARGPPARDPPARA
SCHEMBL9500045 0.79 GGPS1 (0.50) KMT2AGPR84PPARGPPARDPPARA
SCHEMBL9153322 0.79 GGPS1 (0.50) KMT2AGPR84PPARGPPARDPPARA
SCHEMBL2184017 0.79 TDP1 (0.41) KMT2ATSHRALDH1A1TDP1MEN1
SCHEMBL337569 0.79 GGPS1 (0.50) KMT2AGPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824472-A novel method for synthesizing gem-difluoroalkane and α -fluorocarboxylic acid 南京工业大学 2019-05-31 CN disclosed