Trifluoroacetamide

Trifluoroacetamide

SCHEMBL28303100

CC1CCCC[Si]1(C)C.CC1CCCC[Si]1(C)C.NC(=O)C(F)(F)F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetamide SCHEMBL27294990 1.00 EPHX1 (0.33) EPHX1GAATSHRSMN1; SMN2HSD17B10
Trifluoroacetic Acid SCHEMBL28657400 0.87 GAA (0.32) GAATSHRSMN1; SMN2HSD17B10
Urea SCHEMBL27294645 0.87 EPHX1 (0.39) EPHX1GAATSHRSMN1; SMN2HSD17B10
SCHEMBL27783870 0.86 EPHX1 (0.33) EPHX1GAATSHRSMN1; SMN2HSD17B10
Acetamide SCHEMBL27277672 0.85 EPHX1 (0.38) EPHX1GAATSHR
Acetamide SCHEMBL28175715 0.85 EPHX1 (0.38) EPHX1GAATSHR
Oxalic Acid SCHEMBL28847398 0.79 GAA (0.36) EPHX1GAATSHRSMN1; SMN2HSD17B10
Acetic Acid SCHEMBL27395973 0.79 GAA (0.36) EPHX1GAATSHRSMN1; SMN2HSD17B10
Chloromethane SCHEMBL27283470 0.78
Hydrogen Peroxide SCHEMBL27484706 0.78 GAA (0.32) GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110373345-A DEHP hydrolase and gene and its application in the degradation of phthalate plasticiser 华东理工大学 2019-10-25 CN disclosed
CN-109799296-A A kind of sample-pretreating method for the non-targeted metabonomic analysis of cell 江南大学 2019-05-24 CN disclosed