Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.91 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | RET | P07949 | 2/20 | 0.59 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.59 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.59 |
| ▸ | CIT | O14578 | 1/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.54 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.54 |
| ▸ | STK10 | O94804 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | YES1 | P07947 | 1/20 | 0.54 |
| ▸ | LYN | P07948 | 1/20 | 0.54 |
| ▸ | HCK | P08631 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28305035 | 0.96 | KDR (0.98) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL426623 | 0.95 | KDR (1.00) | KDRABCB1RETMAP3K20RIPK3 | |
| Hydrochloric Acid SCHEMBL449929 | 0.94 | KDR (0.98) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL447950 | 0.79 | KDR (1.00) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL429452 | 0.79 | KDR (1.00) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL31362715 | 0.79 | KDR (0.79) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL446863 | 0.79 | KDR (0.79) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL427607 | 0.79 | KDR (0.77) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL450350 | 0.78 | KDR (0.81) | KDRABCB1RETMAP3K20RIPK3 | |
| SCHEMBL426605 | 0.78 | KDR (1.00) | KDRABCB1RETMAP3K20RIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879805-B | Preparation method of apatinib | 苏州富士莱医药股份有限公司 | 2020-08-07 | — | — | CN | claimed |
| CN-109879805-A | A Pa replaces the preparation method of Buddhist nun | 苏州富士莱医药股份有限公司 | 2019-06-14 | — | — | CN | claimed |
| CN-109879805-B | Preparation method of apatinib | 苏州富士莱医药股份有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-109879805-A | A Pa replaces the preparation method of Buddhist nun | 苏州富士莱医药股份有限公司 | 2019-06-14 | — | — | CN | disclosed |