Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224393 | 0.75 | MAP3K12 (0.53) | MAP3K12 | |
| SCHEMBL16212144 | 0.74 | MAP3K12 (0.53) | MAP3K12 | |
| SCHEMBL20147248 | 0.74 | MAP3K12 (0.57) | MAP3K12 | |
| SCHEMBL16211734 | 0.71 | MAP3K12 (0.51) | MAP3K12 | |
| SCHEMBL22098504 | 0.71 | MAP3K12 (0.64) | MAP3K12 | |
| SCHEMBL16211762 | 0.67 | MAP3K12 (0.75) | MAP3K12 | |
| SCHEMBL17510332 | 0.67 | MAP3K12 (0.78) | MAP3K12 | |
| SCHEMBL31674898 | 0.66 | MAP3K12 (1.00) | MAP3K12 | |
| SCHEMBL16224420 | 0.66 | MAP3K12 (1.00) | MAP3K12 | |
| SCHEMBL16224474 | 0.66 | MAP3K12 (0.65) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003178-A | Two heteroaryl compounds and application thereof | 豪夫迈·罗氏有限公司 | 2019-07-12 | — | — | CN | disclosed |