⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2829402 | 0.84 | — | — | |
| SCHEMBL1664585 | 0.82 | — | — | |
| SCHEMBL2827352 | 0.77 | — | — | |
| SCHEMBL27906870 | 0.72 | — | — | |
| SCHEMBL114067 | 0.65 | — | — | |
| SCHEMBL513152 | 0.63 | — | — | |
| SCHEMBL6249697 | 0.63 | — | — | |
| SCHEMBL9053554 | 0.61 | — | — | |
| SCHEMBL2141099 | 0.61 | TDP1 (0.40) | — | |
| SCHEMBL10079878 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238131-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - Portela & Ca., S.A. (PT) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009084970-A1 | 5-O-SUBSTITUTED 3-N-PHENYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL-PORTELA & COMPANHIA, S.A. (PT) | 2009-07-09 | — | — | WO | disclosed |