Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452680 | 0.84 | — | — | |
| Acetic Acid SCHEMBL8461499 | 0.83 | FFAR3 (0.47) | ALDH1A1FFAR3LCKFYN | |
| SCHEMBL30404213 | 0.80 | — | — | |
| SCHEMBL28106566 | 0.80 | — | — | |
| SCHEMBL28115778 | 0.76 | — | — | |
| SCHEMBL27895649 | 0.76 | — | — | |
| SCHEMBL27606097 | 0.76 | — | — | |
| SCHEMBL147779 | 0.76 | — | — | |
| Rubidium SCHEMBL4810885 | 0.76 | — | — | |
| SCHEMBL27518306 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109911925-A | A kind of preparation method that rubber is Nano calcium carbonate dedicated | 长沙理工大学 | 2019-06-21 | — | — | CN | disclosed |