⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699870 | 0.74 | — | — | |
| SCHEMBL623621 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL9468071 | 0.72 | — | — | |
| SCHEMBL7683430 | 0.70 | — | — | |
| SCHEMBL10943340 | 0.65 | — | — | |
| SCHEMBL8968193 | 0.65 | — | — | |
| SCHEMBL13980791 | 0.65 | — | — | |
| SCHEMBL11640096 | 0.64 | FFAR3 (0.36) | — | |
| SCHEMBL17916103 | 0.64 | FFAR3 (0.36) | — | |
| SCHEMBL28196271 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108565-B | The N- pyridine yl acetamide derivatives of inhibitor as WNT signal transmission approach | 莱德克斯制药公共有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-106795157-B | The N- pyridine yl acetamide derivatives of inhibitor as Wnt signal transmission approach | 莱德克斯制药公共有限公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-107108565-A | The N pyridine yl acetamide derivatives of the inhibitor of approach are transmitted as WNT signals | 莱德克斯制药公共有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-106795157-A | As the N pyridine yl acetamide derivatives of the inhibitor of Wnt signals transmission approach | 莱德克斯制药公共有限公司 | 2017-05-31 | — | — | CN | disclosed |