Methane

Methane

SCHEMBL28309787

C.C=CCOC(=O)c1ccccc1C(=O)OCC=C

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.96
TSHR P16473 7/20 0.74
ALDH1A1 P00352 5/20 0.74
HSD17B10 Q99714 1/20 0.74
LIG1 P18858 1/20 0.51
RHOA P61586 1/20 0.50
NPC1 O15118 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
MAPK1 P28482 2/20 0.46
TP53 P04637 1/20 0.46
PKM P14618 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SNCA P37840 1/20 0.45
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362146 0.98 CYP3A4 (1.00) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL27474785 0.98 CYP3A4 (1.00) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL15174 0.98 CYP3A4 (1.00) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL16371573 0.98 CYP3A4 (1.00) CYP3A4TSHRALDH1A1HSD17B10LIG1
Phosphine SCHEMBL28202216 0.96 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL27680049 0.96 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL27353775 0.96 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10LIG1
Ethylene SCHEMBL11883084 0.96 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL11394440 0.96 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL11394446 0.96 CYP3A4 (0.96) CYP3A4TSHRALDH1A1HSD17B10LIG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110088233-A Effective curing agent of free-radical crosslinkable polymers 阿科玛股份有限公司 2019-08-02 CN disclosed