SCHEMBL28309934

SCHEMBL28309934

C=C(c1ccccc1)c1ccc([SiH](C(C)C)C(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 4/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
LMNA P02545 3/20 0.40
NPSR1 Q6W5P4 3/20 0.40
XBP1 P17861 2/20 0.40
ATM Q13315 2/20 0.40
HTT P42858 2/20 0.37
GFER P55789 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
DAO P14920 1/20 0.33
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28668945 0.92 MAPT (0.42) MEN1KMT2AMAPTHTTGFER
SCHEMBL29364608 0.80 KMT2A (0.58) MEN1KMT2AMAPTHTTGFER
SCHEMBL28309937 0.78 MEN1 (0.53) MEN1KMT2AMAPTSMN1; SMN2LMNA
SCHEMBL28310666 0.77 MEN1 (0.48) MEN1KMT2AMAPTSMN1; SMN2LMNA
SCHEMBL380702 0.76 TDP1 (0.36) LMNAATMHSD17B10ALDH1A1L3MBTL1
SCHEMBL894135 0.76 MEN1 (0.65) MEN1KMT2AMAPTSMN1; SMN2LMNA
SCHEMBL2982165 0.75 TSHR (0.55) KMT2ASMN1; SMN2ALDH1A1HPGDCES2
SCHEMBL28310670 0.74 MEN1 (0.46) MEN1KMT2AMAPTSMN1; SMN2LMNA
Fluoride SCHEMBL27639901 0.74 TDP1 (0.35) LMNAALDH1A1TSHR
SCHEMBL6547367 0.74 MEN1 (0.53) MEN1KMT2AMAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115536762-B Liquid crystal grafted modified polystyrene with wide liquid crystal temperature range, differential photoresponse and reversible isomerization and preparation method thereof 大连理工大学 2024-06-14 CN claimed
CN-115536762-A Differential photoresponse and isomerization reversible liquid crystal grafted modified polystyrene with wide liquid crystal temperature domain and preparation method thereof 大连理工大学 2022-12-30 CN claimed
CN-110105498-B Mono-silicon-hydrogen functionalized star polymer suitable for hydrosilylation chemical reaction and preparation method thereof 大连理工大学 2021-07-30 CN claimed
CN-110105498-A One kind is suitable for single silicon hydrogen functionalization star polymer and preparation method thereof of Si―H addition reaction chemical reaction 大连理工大学 2019-08-09 CN claimed
CN-115536762-B Liquid crystal grafted modified polystyrene with wide liquid crystal temperature range, differential photoresponse and reversible isomerization and preparation method thereof 大连理工大学 2024-06-14 CN disclosed
CN-113980215-B HIPS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113831478-B ABS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113999355-B HIPS resin containing DPE derivative, butadiene and styrene star copolymer blocks and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113980214-B ABS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2023-04-28 CN disclosed
CN-113912798-B Star block copolymer based on DPE derivatives, butadiene, isoprene and styrene monomers and preparation method thereof 大连理工大学 2023-03-24 CN disclosed
CN-115536762-A Differential photoresponse and isomerization reversible liquid crystal grafted modified polystyrene with wide liquid crystal temperature domain and preparation method thereof 大连理工大学 2022-12-30 CN disclosed
CN-113817111-B Soluble polymerized A-DPE derivative SIBR star-shaped integrated rubber toughened HIPS resin and preparation method thereof 大连理工大学 2022-11-11 CN disclosed
CN-113980214-A ABS resin containing DPE derivative, butadiene and styrene star copolymer block and preparation method thereof 大连理工大学 2022-01-28 CN disclosed
CN-113912797-A DPE derivative, butadiene and styrene star block copolymer and preparation method thereof 大连理工大学 2022-01-11 CN disclosed
CN-113912798-A Star block copolymer based on DPE derivatives, butadiene, isoprene and styrene monomers and preparation method thereof 大连理工大学 2022-01-11 CN disclosed
CN-113831478-A ABS resin containing DPE derivative, butadiene, isoprene and styrene star copolymer block and preparation method thereof 大连理工大学 2021-12-24 CN disclosed
CN-113817111-A Soluble polymerized A-DPE derivative SIBR star-shaped integrated rubber toughened HIPS resin and preparation method thereof 大连理工大学 2021-12-21 CN disclosed
CN-113698543-A Soluble polymerized A-DPE derivative SIBR integrated rubber toughened ABS resin and preparation method thereof 大连理工大学 2021-11-26 CN disclosed
CN-113698542-A Soluble polymerized A-DPE derivative SIBR star-shaped integrated rubber toughened ABS resin and preparation method thereof 大连理工大学 2021-11-26 CN disclosed
CN-110105498-B Mono-silicon-hydrogen functionalized star polymer suitable for hydrosilylation chemical reaction and preparation method thereof 大连理工大学 2021-07-30 CN disclosed